SymSitive* is a soothing ingredient for sensitive skin. With its neurosensory activity, SymSitive* provides instant and long-lasting relief from stinging, burning, and itching. Skin discomfort like tingling, burning and itching is characterized by a hyperresponsiveness of sensory neurons and stimulation of the thermoreceptor TRPV1 (capsaicin receptor). 

The Nobel Prize in Physiology and Medicine 2021 was awarded to David Julius and Ardem Patapoutian for the discovery of temperature receptor such as TRPV1.

SymSitive* acts on the Nobel Prize awarded mode of action of TRPV1 actively soothes the feeling of tingling, itching and burning.

*registered trademark of Symrise, Germany

Licochalcone A is a potent anti-inflammatory and antioxidant active that is derived from the roots of the Chinese licorice plant Glycyrrhiza inflata. Licochalcone A protects cells from oxidative stress mediated by UV and blue light (HEVIS).

Licochalcone A is able to activate anti-inflammatory, antioxidant and detoxifying enzymes. These enzymes protect the skin cells from damage induced by oxidative stress, like lipid peroxidation and DNA as wells as protein damage. Licochalcone A is able to soothe irritated skin and redness.